In vivo antitumor activity of PHT-427 inhibitor-loaded polymeric nanoparticles in head and neck squa...
In vivo antitumor activity of PHT-427 inhibitor-loaded polymeric nanoparticles in head and neck squamous cell carcinoma
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England: Taylor & Francis
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Language
English
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England: Taylor & Francis
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Recent studies on head and neck squamous cell carcinoma (HNSCC) tumorigenesis have revealed several dysregulated molecular pathways. The phosphatidylinositol-3-kinase (PI3K) signaling pathway is frequently activated in HNSCC, making it an attractive target for therapies. PHT-427 is a dual inhibitor of PI3K and the mammalian target of AKT/PDK1. This...
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In vivo antitumor activity of PHT-427 inhibitor-loaded polymeric nanoparticles in head and neck squamous cell carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_a36f88d73d404e40afa60f7760f3d7ab
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a36f88d73d404e40afa60f7760f3d7ab
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ISSN
1071-7544,1521-0464
E-ISSN
1521-0464
DOI
10.1080/10717544.2024.2449376
