Integrated genetic and pharmacologic interrogation of rare cancers
Integrated genetic and pharmacologic interrogation of rare cancers
About this item
Full title
Author / Creator
Hong, Andrew L. , Tseng, Yuen-Yi , Cowley, Glenn S. , Jonas, Oliver , Cheah, Jaime H. , Kynnap, Bryan D. , Doshi, Mihir B. , Oh, Coyin , Meyer, Stephanie C. , Church, Alanna J. , Gill, Shubhroz , Bielski, Craig M. , Keskula, Paula , Imamovic, Alma , Howell, Sara , Kryukov, Gregory V. , Clemons, Paul A. , Tsherniak, Aviad , Vazquez, Francisca , Crompton, Brian D. , Shamji, Alykhan F. , Rodriguez-Galindo, Carlos , Janeway, Katherine A. , Roberts, Charles W. M. , Stegmaier, Kimberly , van Hummelen, Paul , Cima, Michael J. , Langer, Robert S. , Garraway, Levi A. , Schreiber, Stuart L. , Root, David E. , Hahn, William C. and Boehm, Jesse S.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Identifying therapeutic targets in rare cancers remains challenging due to the paucity of established models to perform preclinical studies. As a proof-of-concept, we developed a patient-derived cancer cell line, CLF-PED-015-T, from a paediatric patient with a rare undifferentiated sarcoma. Here, we confirm that this cell line recapitulates the his...
Alternative Titles
Full title
Integrated genetic and pharmacologic interrogation of rare cancers
Authors, Artists and Contributors
Author / Creator
Tseng, Yuen-Yi
Cowley, Glenn S.
Jonas, Oliver
Cheah, Jaime H.
Kynnap, Bryan D.
Doshi, Mihir B.
Oh, Coyin
Meyer, Stephanie C.
Church, Alanna J.
Gill, Shubhroz
Bielski, Craig M.
Keskula, Paula
Imamovic, Alma
Howell, Sara
Kryukov, Gregory V.
Clemons, Paul A.
Tsherniak, Aviad
Vazquez, Francisca
Crompton, Brian D.
Shamji, Alykhan F.
Rodriguez-Galindo, Carlos
Janeway, Katherine A.
Roberts, Charles W. M.
Stegmaier, Kimberly
van Hummelen, Paul
Cima, Michael J.
Langer, Robert S.
Garraway, Levi A.
Schreiber, Stuart L.
Root, David E.
Hahn, William C.
Boehm, Jesse S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a374f09a5d1640b381b40c1ebaec01db
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a374f09a5d1640b381b40c1ebaec01db
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11987
