Genomic landscape and chronological reconstruction of driver events in multiple myeloma
Genomic landscape and chronological reconstruction of driver events in multiple myeloma
About this item
Full title
Author / Creator
Maura, Francesco , Bolli, Niccoló , Angelopoulos, Nicos , Dawson, Kevin J. , Leongamornlert, Daniel , Martincorena, Inigo , Mitchell, Thomas J. , Fullam, Anthony , Gonzalez, Santiago , Szalat, Raphael , Abascal, Federico , Rodriguez-Martin, Bernardo , Samur, Mehmet Kemal , Glodzik, Dominik , Roncador, Marco , Fulciniti, Mariateresa , Tai, Yu Tzu , Minvielle, Stephane , Magrangeas, Florence , Moreau, Philippe , Corradini, Paolo , Anderson, Kenneth C. , Tubio, Jose M. C. , Wedge, David C. , Gerstung, Moritz , Avet-Loiseau, Hervé , Munshi, Nikhil and Campbell, Peter J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The multiple myeloma (MM) genome is heterogeneous and evolves through preclinical and post-diagnosis phases. Here we report a catalog and hierarchy of driver lesions using sequences from 67 MM genomes serially collected from 30 patients together with public exome datasets. Bayesian clustering defines at least 7 genomic subgroups with distinct sets...
Alternative Titles
Full title
Genomic landscape and chronological reconstruction of driver events in multiple myeloma
Authors, Artists and Contributors
Author / Creator
Bolli, Niccoló
Angelopoulos, Nicos
Dawson, Kevin J.
Leongamornlert, Daniel
Martincorena, Inigo
Mitchell, Thomas J.
Fullam, Anthony
Gonzalez, Santiago
Szalat, Raphael
Abascal, Federico
Rodriguez-Martin, Bernardo
Samur, Mehmet Kemal
Glodzik, Dominik
Roncador, Marco
Fulciniti, Mariateresa
Tai, Yu Tzu
Minvielle, Stephane
Magrangeas, Florence
Moreau, Philippe
Corradini, Paolo
Anderson, Kenneth C.
Tubio, Jose M. C.
Wedge, David C.
Gerstung, Moritz
Avet-Loiseau, Hervé
Munshi, Nikhil
Campbell, Peter J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a38608a486ef471e8da57b4ab94d19b3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a38608a486ef471e8da57b4ab94d19b3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11680-1
