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Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a391b04c6a3242c3a64fb5dbffab3422

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

About this item

Full title

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2015-06, Vol.7 (6), p.802-818

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The metabolic syndrome covers metabolic abnormalities including obesity and type 2 diabetes (T2D). T2D is characterized by insulin resistance resulting from both environmental and genetic factors. A genome‐wide association study (GWAS) published in 2010 identified
TP53INP1
as a new T2D susceptibility locus, but a pathological mechanism was no...

Alternative Titles

Full title

Defects in mitophagy promote redox‐driven metabolic syndrome in the absence of TP53INP1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a391b04c6a3242c3a64fb5dbffab3422

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a391b04c6a3242c3a64fb5dbffab3422

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201404318

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