Profile of asfotase alfa in the treatment of hypophosphatasia: design, development, and place in the...
Profile of asfotase alfa in the treatment of hypophosphatasia: design, development, and place in therapy
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Publisher
New Zealand: Dove Medical Press Limited
Journal title
Language
English
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Publisher
New Zealand: Dove Medical Press Limited
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Contents
Hypophosphatasia (HPP) is a multi-systemic metabolic disorder caused by loss-of-function mutations in the
gene that encodes the mineralization-associated enzyme, tissue-nonspecific alkaline phosphatase (TNSALP). HPP is characterized by defective bone and dental mineralization, leading to skeletal abnormalities with complications resulting in sig...
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Full title
Profile of asfotase alfa in the treatment of hypophosphatasia: design, development, and place in therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_a3a90e0441164385921d556fb848030e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a3a90e0441164385921d556fb848030e
Other Identifiers
ISSN
1177-8881
E-ISSN
1177-8881
DOI
10.2147/DDDT.S154922
