Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligom...
Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Transactive response DNA-binding protein 43 (TDP-43) is the pathological protein found in frontotemporal lobar degeneration with ubiquitin positive inclusions and in amyotrophic lateral sclerosis. In diseased tissue, TDP-43 translocates from its physiological nuclear location into the cytoplasm, where it accumulates. Additionally, C-terminal fragme...
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Full title
Age-dependent changes in TDP-43 levels in a mouse model of Alzheimer disease are linked to Aβ oligomers accumulation
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TN_cdi_doaj_primary_oai_doaj_org_article_a3a9f6ad7a3d4df0ae8686ad2863e456
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a3a9f6ad7a3d4df0ae8686ad2863e456
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ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/1750-1326-5-51
