A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Infla...
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation
About this item
Full title
Author / Creator
Corvino, Angela , Granato, Elisabetta , Scognamiglio, Antonia , Fiorino, Ferdinando , Frecentese, Francesco , Magli, Elisa , Perissutti, Elisa , Santagada, Vincenzo , Cirino, Giuseppe , Cerqua, Ida , Pavese, Rocco , Petti, Antonio , Pavese, Francesca , Petti, Francesco , Roviezzo, Fiorentina , Severino, Beatrice and Caliendo, Giuseppe
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
In this study, a new and straightforward process for the preparation of budesonide 21-phosphate (Bud-21P) and its disodium salt (Bud-21P-Na2) is described. The method results in a yield comparable to those obtained by diphosphoryl chloride, but it is more manageable, less expensive, and safer. The new compounds are characterized by better water sol...
Alternative Titles
Full title
A New Process for the Synthesis of Budesonide 21-Phosphate and Evaluation in a Murine Model of Inflammation
Authors, Artists and Contributors
Author / Creator
Granato, Elisabetta
Scognamiglio, Antonia
Fiorino, Ferdinando
Frecentese, Francesco
Magli, Elisa
Perissutti, Elisa
Santagada, Vincenzo
Cirino, Giuseppe
Cerqua, Ida
Pavese, Rocco
Petti, Antonio
Pavese, Francesca
Petti, Francesco
Roviezzo, Fiorentina
Severino, Beatrice
Caliendo, Giuseppe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a3abcecee4cf44e68dc1c62fe07cd798
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a3abcecee4cf44e68dc1c62fe07cd798
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules29184514
