[18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease patho...
[18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice
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Berlin/Heidelberg: Springer Berlin Heidelberg
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English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Background
Oxidative stress is implicated in the pathogenesis of the most common neurodegenerative diseases, such as Alzheimer’s disease (AD). However, tracking oxidative stress in the brain has proven difficult and impeded its use as a biomarker. Herein, we investigate the utility of a novel positron emission tomography (PET) tracer, [
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[18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice
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TN_cdi_doaj_primary_oai_doaj_org_article_a3b82024f10c4b7c8060ea62d1e48ada
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a3b82024f10c4b7c8060ea62d1e48ada
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ISSN
2191-219X
E-ISSN
2191-219X
DOI
10.1186/s13550-022-00914-x
