Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation
Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation
About this item
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Author / Creator
Misheva, Mariya , Kotzamanis, Konstantinos , Davies, Luke C. , Tyrrell, Victoria J. , Rodrigues, Patricia R. S. , Benavides, Gloria A. , Hinz, Christine , Murphy, Robert C. , Kennedy, Paul , Taylor, Philip R. , Rosas, Marcela , Jones, Simon A. , McLaren, James E. , Deshpande, Sumukh , Andrews, Robert , Schebb, Nils Helge , Czubala, Magdalena A. , Gurney, Mark , Aldrovandi, Maceler , Meckelmann, Sven W. , Ghazal, Peter , Darley-Usmar, Victor , White, Daniel A. and O’Donnell, Valerie B.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Oxylipins are potent biological mediators requiring strict control, but how they are removed en masse during infection and inflammation is unknown. Here we show that lipopolysaccharide (LPS) dynamically enhances oxylipin removal via mitochondrial β-oxidation. Specifically, genetic or pharmacological targeting of carnitine palmitoyl transferase 1 (C...
Alternative Titles
Full title
Oxylipin metabolism is controlled by mitochondrial β-oxidation during bacterial inflammation
Authors, Artists and Contributors
Author / Creator
Kotzamanis, Konstantinos
Davies, Luke C.
Tyrrell, Victoria J.
Rodrigues, Patricia R. S.
Benavides, Gloria A.
Hinz, Christine
Murphy, Robert C.
Kennedy, Paul
Taylor, Philip R.
Rosas, Marcela
Jones, Simon A.
McLaren, James E.
Deshpande, Sumukh
Andrews, Robert
Schebb, Nils Helge
Czubala, Magdalena A.
Gurney, Mark
Aldrovandi, Maceler
Meckelmann, Sven W.
Ghazal, Peter
Darley-Usmar, Victor
White, Daniel A.
O’Donnell, Valerie B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a3d11671abcf4409a6bdffc0da87c0f3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a3d11671abcf4409a6bdffc0da87c0f3
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-27766-8
