Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implica...
Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer
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Author / Creator
Wang, Jingyuan , Xiu, Joanne , Battaglin, Francesca , Arai, Hiroyuki , Soni, Shivani , Zhang, Wu , Goldberg, Richard M. , Philip, Philip A. , Seeber, Andreas , Hwang, Jimmy J. , Shields, Anthony F. , Marshall, John L. , Astaturov, Igor , Liu, Tianshu , Lockhart, A. Craig , Korn, W. Michael , Shen, Lin and Lenz, Heinz-Josef
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Although histological and molecular classifications have been extensively studied for gastric cancer (GC), targeted therapies for GC remain limited.
CDH1
mutations (MT) are characteristic of genomically stable GC and are associated with poor prognosis, but lack effective or targeted therapies. Here, we showed the overall mutation frequency of...
Alternative Titles
Full title
Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_a3d469c1d6cf430091e90de7ea2adb8c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a3d469c1d6cf430091e90de7ea2adb8c
Other Identifiers
ISSN
2397-768X
E-ISSN
2397-768X
DOI
10.1038/s41698-024-00694-8
