Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheim...
Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA
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Author / Creator
Mao, Sanying , Zhao, Xiyao , Wang, Lei , Man, Yilong and Li, Kaiyuan
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
The mechanism of palmitoylation in the pathogenesis of Alzheimer's disease (AD) remains unclear.
This study retrieved AD data sets from the GEO database to identify palmitoylation-associated genes (PRGs). This study applied WGCNA along with three machine learning algorithms-random forest, LASSO regression, and SVM-RFE-to further select key PRGs...
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Full title
Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a4142981f51045f5896e6e4f594638fc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4142981f51045f5896e6e4f594638fc
Other Identifiers
ISSN
2047-783X,0949-2321
E-ISSN
2047-783X
DOI
10.1186/s40001-025-02277-0
