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Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction

Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a42dfe66f023464695a745dd11c12ea6

Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction

About this item

Full title

Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction

Publisher

England: BioMed Central Ltd

Journal title

Immunity & ageing, 2024-07, Vol.21 (1), p.45-16, Article 45

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The function of polymorphonuclear neutrophils (PMNs) decreases with age, which results in infectious and inflammatory complications in older individuals. The underlying causes are not fully understood. ATP release and autocrine stimulation of purinergic receptors help PMNs combat microbial invaders. Excessive extracellular ATP interferes with these...

Alternative Titles

Full title

Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a42dfe66f023464695a745dd11c12ea6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a42dfe66f023464695a745dd11c12ea6

Other Identifiers

ISSN

1742-4933

E-ISSN

1742-4933

DOI

10.1186/s12979-024-00441-4

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