Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction
Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The function of polymorphonuclear neutrophils (PMNs) decreases with age, which results in infectious and inflammatory complications in older individuals. The underlying causes are not fully understood. ATP release and autocrine stimulation of purinergic receptors help PMNs combat microbial invaders. Excessive extracellular ATP interferes with these...
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Full title
Impaired ATP hydrolysis in blood plasma contributes to age-related neutrophil dysfunction
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TN_cdi_doaj_primary_oai_doaj_org_article_a42dfe66f023464695a745dd11c12ea6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a42dfe66f023464695a745dd11c12ea6
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ISSN
1742-4933
E-ISSN
1742-4933
DOI
10.1186/s12979-024-00441-4