Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters
Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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α-ketoglutarate (KG), also referred to as 2-oxoglutarate, is a key intermediate of cellular metabolism with pleiotropic functions. Cell-permeable esterified analogs are widely used to study how KG fuels bioenergetic and amino acid metabolism and DNA, RNA, and protein hydroxylation reactions, as cellular membranes are thought to be impermeable to KG...
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Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters
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TN_cdi_doaj_primary_oai_doaj_org_article_a430c84ac3014555b5b20af966982f02
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a430c84ac3014555b5b20af966982f02
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25228-9
