Human cortical spheroids with a high diversity of innately developing brain cell types
Human cortical spheroids with a high diversity of innately developing brain cell types
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Three-dimensional (3D) human brain spheroids are instrumental to study central nervous system (CNS) development and (dys)function. Yet, in current brain spheroid models the limited variety of cell types hampers an integrated exploration of CNS (disease) mechanisms.
Here we report a 5-month culture protocol that reproducibly generates H9 embryoni...
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Human cortical spheroids with a high diversity of innately developing brain cell types
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TN_cdi_doaj_primary_oai_doaj_org_article_a4405140e35247bb8156819432f89c24
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4405140e35247bb8156819432f89c24
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ISSN
1757-6512
E-ISSN
1757-6512
DOI
10.1186/s13287-023-03261-3