Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity
Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial
β
-trefoil lectin that recognises Burkitt’s lymphoma cells, and which was designed with the intention of finding a basis for novel cancer trea...
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Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity
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TN_cdi_doaj_primary_oai_doaj_org_article_a440be7c963c4aa4b4ba9fc614b1d221
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a440be7c963c4aa4b4ba9fc614b1d221
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-06332-7