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Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a440be7c963c4aa4b4ba9fc614b1d221

Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

About this item

Full title

Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-07, Vol.7 (1), p.5943-13, Article 5943

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial
β
-trefoil lectin that recognises Burkitt’s lymphoma cells, and which was designed with the intention of finding a basis for novel cancer trea...

Alternative Titles

Full title

Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a440be7c963c4aa4b4ba9fc614b1d221

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a440be7c963c4aa4b4ba9fc614b1d221

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-06332-7

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