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Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance i...

Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a45a8ccd572d4e26bbdb9fa4a29deaec

Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population

About this item

Full title

Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2020-02, Vol.10 (1), p.3282-3282, Article 3282

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Since antibiotic resistance is a major threat to global health, recent observations that the traditional test of minimum inhibitory concentration (MIC) is not informative enough to guide effective antibiotic treatment are alarming. Bacterial heteroresistance, in which seemingly susceptible isogenic bacterial populations contain resistant sub-popula...

Alternative Titles

Full title

Droplet-based digital antibiotic susceptibility screen reveals single-cell clonal heteroresistance in an isogenic bacterial population

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a45a8ccd572d4e26bbdb9fa4a29deaec

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a45a8ccd572d4e26bbdb9fa4a29deaec

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-020-60381-z

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