In vivo gene editing of T-cells in lymph nodes for enhanced cancer immunotherapy
In vivo gene editing of T-cells in lymph nodes for enhanced cancer immunotherapy
About this item
Full title
Author / Creator
Qu, Jin , Wang, Yuan , Xiong, Chuxiao , Wang, Mingxue , He, Xingdao , Jia, Weibin , Li, Cheuk Yin , Zhang, Tianlong , Wang, Zixun , Li, Wei , Kuang, Becki Yi and Shi, Peng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Immune checkpoint blockade (ICB) therapy, while promising for cancer treatment, faces challenges like unexpected side effects and limited objective responses. Here, we develop an in vivo gene-editing strategy for improving ICB cancer therapy in a lastingly effective manner. The approach uses a conductive hydrogel-based electroporation system to ena...
Alternative Titles
Full title
In vivo gene editing of T-cells in lymph nodes for enhanced cancer immunotherapy
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a45bab9f0c7c40549d8a8e904504777f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a45bab9f0c7c40549d8a8e904504777f
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-54292-0
