Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin sy...
Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system
About this item
Full title
Author / Creator
Weigert, Andreas , Zheng, Xiang , Nenzel, Alina , Turkowski, Kati , Günther, Stefan , Strack, Elisabeth , Sirait-Fischer, Evelyn , Elwakeel, Eiman , Kur, Ivan M. , Nikam, Vandana S. , Valasarajan, Chanil , Winter, Hauke , Wissgott, Alexander , Voswinkel, Robert , Grimminger, Friedrich , Brüne, Bernhard , Seeger, Werner , Pullamsetti, Soni Savai and Savai, Rajkumar
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Fibrocytes are bone marrow–derived monocytic cells implicated in wound healing. Here, we identify their role in lung cancer progression/ metastasis. Selective manipulation of fibrocytes in mouse lung tumor models documents the central role of fibrocytes in boosting niche features and enhancing metastasis. Importantly, lung cancer patients show incr...
Alternative Titles
Full title
Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system
Authors, Artists and Contributors
Author / Creator
Zheng, Xiang
Nenzel, Alina
Turkowski, Kati
Günther, Stefan
Strack, Elisabeth
Sirait-Fischer, Evelyn
Elwakeel, Eiman
Kur, Ivan M.
Nikam, Vandana S.
Valasarajan, Chanil
Winter, Hauke
Wissgott, Alexander
Voswinkel, Robert
Grimminger, Friedrich
Brüne, Bernhard
Seeger, Werner
Pullamsetti, Soni Savai
Savai, Rajkumar
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a45ef476278744d49bbf2334b639d6fb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a45ef476278744d49bbf2334b639d6fb
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-33458-8
