Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5...
Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5+ cochlear spiral ganglion neurons in vitro
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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SGNs are the primary auditory neurons, and damage or loss of SGNs leads to sensorineural hearing loss. BMP4 is a growth factor that belongs to the TGF-β superfamily and has been shown to play a key role during development, but little is known about its effect on postnatal cochlear SGNs in mice. In this study, we used the P3 Bhlhb5-cre/tdTomato tran...
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Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5+ cochlear spiral ganglion neurons in vitro
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TN_cdi_doaj_primary_oai_doaj_org_article_a48764753ef04360a476c81629882cc4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a48764753ef04360a476c81629882cc4
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ISSN
2045-2322
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2045-2322
DOI
10.1038/s41598-017-03810-w
