A genome-wide screen identifies genes required for erythroid differentiation
A genome-wide screen identifies genes required for erythroid differentiation
About this item
Full title
Author / Creator
Myers, Greggory , Friedman, Ann , Yu, Lei , Pourmandi, Narges , Kerpet, Claire , Ito, Masaki A. , Saba, Rilie , Tang, Vi , Ozel, Ayse Bilge , Bergin, Ingrid L. , Johnson, Craig N. , Ku, Chia-Jui , Wang, Yu , Balbin-Cuesta, Ginette , Lim, Kim-Chew , Lin, Zesen , Drysdale, Claire , McGee, Beth , Kurita, Ryo , Nakamura, Yukio , Liu, Xiaofang , Siemieniak, David , Singh, Sharon A. , Lyssiotis, Costas A. , Maillard, Ivan , Weisman, Lois S. , Engel, James Douglas and Khoriaty, Rami
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The complete array of genes required for terminal erythroid differentiation remains unknown. To address this knowledge gap, we perform a genome-scale CRISPR knock-out screen in the human erythroid progenitor cell line HUDEP-2 and validate candidate regulators of erythroid differentiation in a custom secondary screen. Comparison of sgRNA abundance i...
Alternative Titles
Full title
A genome-wide screen identifies genes required for erythroid differentiation
Authors, Artists and Contributors
Author / Creator
Friedman, Ann
Yu, Lei
Pourmandi, Narges
Kerpet, Claire
Ito, Masaki A.
Saba, Rilie
Tang, Vi
Ozel, Ayse Bilge
Bergin, Ingrid L.
Johnson, Craig N.
Ku, Chia-Jui
Wang, Yu
Balbin-Cuesta, Ginette
Lim, Kim-Chew
Lin, Zesen
Drysdale, Claire
McGee, Beth
Kurita, Ryo
Nakamura, Yukio
Liu, Xiaofang
Siemieniak, David
Singh, Sharon A.
Lyssiotis, Costas A.
Maillard, Ivan
Weisman, Lois S.
Engel, James Douglas
Khoriaty, Rami
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a4b3dbed174840db95690033ec40db4e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4b3dbed174840db95690033ec40db4e
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-58739-w
