Optogenetic manipulation of Gq- and Gi/o-coupled receptor signaling in neurons and heart muscle cell...
Optogenetic manipulation of Gq- and Gi/o-coupled receptor signaling in neurons and heart muscle cells
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Cambridge: eLife Sciences Publications Ltd
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English
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Cambridge: eLife Sciences Publications Ltd
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G-protein-coupled receptors (GPCRs) transmit signals into cells depending on the G protein type. To analyze the functions of GPCR signaling, we assessed the effectiveness of animal G-protein-coupled bistable rhodopsins that can be controlled into active and inactive states by light application using zebrafish. We expressed Gq- and Gi/o-coupled bist...
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Optogenetic manipulation of Gq- and Gi/o-coupled receptor signaling in neurons and heart muscle cells
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TN_cdi_doaj_primary_oai_doaj_org_article_a4d2f0bc6e104590a7e2dd56d30dbabe
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4d2f0bc6e104590a7e2dd56d30dbabe
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.83974