ER stress regulates alkaline phosphatase gene expression in vascular smooth muscle cells via an ATF4...
ER stress regulates alkaline phosphatase gene expression in vascular smooth muscle cells via an ATF4-dependent mechanism
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Publisher
England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Vascular calcification is the deposition of hydroxyapatite crystals in the blood vessel wall. Osteogenic differentiation of vascular smooth muscle cells (VSMCs) plays a key role in this process. Increased expression of alkaline phosphatase (ALP) occurs in some in vitro models of VSMC calcification and is thought to be crucial for mineralization, ho...
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Full title
ER stress regulates alkaline phosphatase gene expression in vascular smooth muscle cells via an ATF4-dependent mechanism
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TN_cdi_doaj_primary_oai_doaj_org_article_a4e6cfe262af43e6957730b74866c4a2
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4e6cfe262af43e6957730b74866c4a2
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ISSN
1756-0500
E-ISSN
1756-0500
DOI
10.1186/s13104-018-3582-4
