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Direct recognition of an intact foreign protein by an αβ T cell receptor

Direct recognition of an intact foreign protein by an αβ T cell receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4fb52352ddb44ba9d2176f3352758f0

Direct recognition of an intact foreign protein by an αβ T cell receptor

About this item

Full title

Direct recognition of an intact foreign protein by an αβ T cell receptor

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-10, Vol.15 (1), p.8816-18, Article 8816

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

αβ T cell receptors (αβTCRs) co-recognise antigens when bound to Major Histocompatibility Complex (MHC) or MHC class I-like molecules. Additionally, some αβTCRs can bind non-MHC molecules, but how much intact antigen reactivities are achieved remains unknown. Here, we identify an αβ T cell clone that directly recognises the intact foreign protein,...

Alternative Titles

Full title

Direct recognition of an intact foreign protein by an αβ T cell receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a4fb52352ddb44ba9d2176f3352758f0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4fb52352ddb44ba9d2176f3352758f0

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-51897-3

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