Direct recognition of an intact foreign protein by an αβ T cell receptor
Direct recognition of an intact foreign protein by an αβ T cell receptor
About this item
Full title
Author / Creator
Almeida, Catarina F. , Gully, Benjamin S. , Jones, Claerwen M. , Kedzierski, Lukasz , Gunasinghe, Sachith D. , Rice, Michael T. , Berry, Richard , Gherardin, Nicholas A. , Nguyen, Trang T. , Mok, Yee-Foong , Reijneveld, Josephine F. , Moody, D. Branch , Van Rhijn, Ildiko , La Gruta, Nicole L. , Uldrich, Adam P. , Rossjohn, Jamie and Godfrey, Dale I.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
αβ T cell receptors (αβTCRs) co-recognise antigens when bound to Major Histocompatibility Complex (MHC) or MHC class I-like molecules. Additionally, some αβTCRs can bind non-MHC molecules, but how much intact antigen reactivities are achieved remains unknown. Here, we identify an αβ T cell clone that directly recognises the intact foreign protein,...
Alternative Titles
Full title
Direct recognition of an intact foreign protein by an αβ T cell receptor
Authors, Artists and Contributors
Author / Creator
Gully, Benjamin S.
Jones, Claerwen M.
Kedzierski, Lukasz
Gunasinghe, Sachith D.
Rice, Michael T.
Berry, Richard
Gherardin, Nicholas A.
Nguyen, Trang T.
Mok, Yee-Foong
Reijneveld, Josephine F.
Moody, D. Branch
Van Rhijn, Ildiko
La Gruta, Nicole L.
Uldrich, Adam P.
Rossjohn, Jamie
Godfrey, Dale I.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a4fb52352ddb44ba9d2176f3352758f0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a4fb52352ddb44ba9d2176f3352758f0
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51897-3