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A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain usi...

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain usi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a50605a064c049859dfcd1fb76a10dad

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing

About this item

Full title

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-07, Vol.11 (1), p.3461-3461, Article 3461

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Leishmaniasis is a neglected tropical disease caused by
Leishmania
protozoa transmitted by infected sand flies. Vaccination through leishmanization with live
Leishmania major
has been used successfully but is no longer practiced because it resulted in occasional skin lesions. A second generation leishmanization is described here using a...

Alternative Titles

Full title

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a50605a064c049859dfcd1fb76a10dad

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a50605a064c049859dfcd1fb76a10dad

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-17154-z

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