Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation...
Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6
About this item
Full title
Author / Creator
Taha, Taha Y. , Ezzatpour, Shahrzad , Hayashi, Jennifer M. , Ye, Chengjin , Zapatero-Belinchón, Francisco J. , Rosecrans, Julia A. , Kimmerly, Gabriella R. , Chen, Irene P. , Walcott, Keith , Kurianowicz, Anna , Jorgens, Danielle M. , Chaplin, Natalie R. , Choi, Annette , Buchholz, David W. , Sahler, Julie , Hilt, Zachary T. , Imbiakha, Brian , Vagi-Szmola, Cecilia , Montano, Mauricio , Stevenson, Erica , Gordon, Martin , Swaney, Danielle L. , Krogan, Nevan J. , Whittaker, Gary R. , Martinez-Sobrido, Luis , Aguilar, Hector C. and Ott, Melanie
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The COVID-19 pandemic has been driven by SARS-CoV-2 variants with enhanced transmission and immune escape. Apart from extensive evolution in the Spike protein, non-Spike mutations are accumulating across the entire viral genome and their functional impact is not well understood. To address the contribution of these mutations, we reconstructed genom...
Alternative Titles
Full title
Enhanced RNA replication and pathogenesis in recent SARS-CoV-2 variants harboring the L260F mutation in NSP6
Authors, Artists and Contributors
Author / Creator
Ezzatpour, Shahrzad
Hayashi, Jennifer M.
Ye, Chengjin
Zapatero-Belinchón, Francisco J.
Rosecrans, Julia A.
Kimmerly, Gabriella R.
Chen, Irene P.
Walcott, Keith
Kurianowicz, Anna
Jorgens, Danielle M.
Chaplin, Natalie R.
Choi, Annette
Buchholz, David W.
Sahler, Julie
Hilt, Zachary T.
Imbiakha, Brian
Vagi-Szmola, Cecilia
Montano, Mauricio
Stevenson, Erica
Gordon, Martin
Swaney, Danielle L.
Krogan, Nevan J.
Whittaker, Gary R.
Martinez-Sobrido, Luis
Aguilar, Hector C.
Ott, Melanie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a51166e237d04db8b53f836d2c6e3737
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a51166e237d04db8b53f836d2c6e3737
Other Identifiers
ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1013020
