Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucle...
Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletion
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England: The Company of Biologists Ltd
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English
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England: The Company of Biologists Ltd
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The proteosome inhibitor bortezomib has revolutionized the treatment of multiple hematologic malignancies, but in many cases, its efficacy is limited by a dose-dependent peripheral neuropathy. We show that human induced pluripotent stem cell (hiPSC)-derived motor neurons and sensory neurons provide a model system for the study of bortezomib-induced...
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Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletion
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TN_cdi_doaj_primary_oai_doaj_org_article_a512aa7304b94a7791b928b38bd35c2b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a512aa7304b94a7791b928b38bd35c2b
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ISSN
1754-8403,1754-8411
E-ISSN
1754-8411
DOI
10.1242/dmm.049358
