Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chain...
Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains
About this item
Full title
Author / Creator
Sternke-Hoffmann, Rebecca , Pauly, Thomas , Norrild, Rasmus K. , Hansen, Jan , Tucholski, Florian , Høie, Magnus Haraldson , Marcatili, Paolo , Dupré, Mathieu , Duchateau, Magalie , Rey, Martial , Malosse, Christian , Metzger, Sabine , Boquoi, Amelie , Platten, Florian , Egelhaaf, Stefan U. , Chamot-Rooke, Julia , Fenk, Roland , Nagel-Steger, Luitgard , Haas, Rainer and Buell, Alexander K.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
In a range of human disorders such as multiple myeloma (MM), immunoglobulin light chains (IgLCs) can be produced at very high concentrations. This can lead to pathological aggregation and deposition of IgLCs in different tissues, which in turn leads to severe and potentially fatal organ damage. However, IgLCs can also be highly soluble and non-toxi...
Alternative Titles
Full title
Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains
Authors, Artists and Contributors
Author / Creator
Pauly, Thomas
Norrild, Rasmus K.
Hansen, Jan
Tucholski, Florian
Høie, Magnus Haraldson
Marcatili, Paolo
Dupré, Mathieu
Duchateau, Magalie
Rey, Martial
Malosse, Christian
Metzger, Sabine
Boquoi, Amelie
Platten, Florian
Egelhaaf, Stefan U.
Chamot-Rooke, Julia
Fenk, Roland
Nagel-Steger, Luitgard
Haas, Rainer
Buell, Alexander K.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a5503dee209f405d8b2875917f0ba3a8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a5503dee209f405d8b2875917f0ba3a8
Other Identifiers
ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/s12915-022-01506-w
