PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding prote...
PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR
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Author / Creator
Ke, Yueshuang , Han, Yanlong , Guo, Xiaolan , Wen, Jitao , Wang, Ke , Jiang, Xue , Tian, Xue , Ba, Xueqing , Boldogh, Istvan and Zeng, Xianlu
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Poly(ADP-ribosyl)ation (PARylation) is mainly catalysed by poly-ADP-ribose polymerase 1 (PARP1), whose role in gene transcription modulation has been well established. Here we show that, in response to LPS exposure, PARP1 interacts with the adenylateuridylate-rich element-binding protein embryonic lethal abnormal vision-like 1 (Elavl1)/human antige...
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Full title
PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR
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TN_cdi_doaj_primary_oai_doaj_org_article_a55d7a2a75e7444fa4ab121ed3fd3490
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a55d7a2a75e7444fa4ab121ed3fd3490
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14632
