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AAV8 vector induced gliosis following neuronal transgene expression

AAV8 vector induced gliosis following neuronal transgene expression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a562754520e34887bbc3e3de81c84cc0

AAV8 vector induced gliosis following neuronal transgene expression

About this item

Full title

AAV8 vector induced gliosis following neuronal transgene expression

Publisher

Switzerland: Frontiers Media S.A

Journal title

Frontiers in neuroscience, 2024, Vol.18, p.1287228

Language

English

Formats

Publication information

Publisher

Switzerland: Frontiers Media S.A

More information

Scope and Contents

Contents

Expression of light sensitive ion channels by selected neurons has been achieved by viral mediated transduction with gene constructs, but for this to have therapeutic uses, for instance in treating epilepsy, any adverse effects of viral infection on the cerebral cortex needs to be evaluated. Here, we assessed the impact of adeno-associated virus 8...

Alternative Titles

Full title

AAV8 vector induced gliosis following neuronal transgene expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a562754520e34887bbc3e3de81c84cc0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a562754520e34887bbc3e3de81c84cc0

Other Identifiers

ISSN

1662-4548,1662-453X

E-ISSN

1662-453X

DOI

10.3389/fnins.2024.1287228

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