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HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells

HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a57a3bc6fa54419b86f08b433c6861ca

HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells

About this item

Full title

HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2019-01, Vol.8 (1), p.45

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The hypoxia-inducible transcription factors (HIF)-1/2α are the main oxygen sensors which regulate the adaptation to intratumoral hypoxia. The aim of this study was to assess the role of the HIF proteins in regulating the radiation response of a non-small cell lung cancer (NSCLC) in vitro model. To directly assess the unique and overlapping function...

Alternative Titles

Full title

HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a57a3bc6fa54419b86f08b433c6861ca

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a57a3bc6fa54419b86f08b433c6861ca

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells8010045

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