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CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis

CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a5e9c2095bb748a4bb7c83c72d6e737d

CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis

About this item

Full title

CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis

Publisher

England: BioMed Central Ltd

Journal title

BMC biology, 2023-05, Vol.21 (1), p.124-124, Article 124

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The axonemal microtubules of primary cilium undergo a conserved protein posttranslational modification (PTM) - polyglutamylation. This reversible procedure is processed by tubulin tyrosine ligase-like polyglutamylases to form secondary polyglutamate side chains, which are metabolized by the 6-member cytosolic carboxypeptidase (CCP) family. Although...

Alternative Titles

Full title

CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a5e9c2095bb748a4bb7c83c72d6e737d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a5e9c2095bb748a4bb7c83c72d6e737d

Other Identifiers

ISSN

1741-7007

E-ISSN

1741-7007

DOI

10.1186/s12915-023-01622-1

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