Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors
Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
CD1a is a monomorphic antigen-presenting molecule on dendritic cells that presents lipids to αβ T cells. Whether CD1a represents a ligand for other immune receptors remains unknown. Here we use CD1a tetramers to show that CD1a is a ligand for Vδ1
+
γδ T cells. Functional studies suggest that two γδ T cell receptors (TCRs) bound CD1a in a lipi...
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Full title
Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors
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TN_cdi_doaj_primary_oai_doaj_org_article_a5eb21242f424541a6a488c362e95bcb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a5eb21242f424541a6a488c362e95bcb
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31443-9
