BARD1 mystery: tumor suppressors are cancer susceptibility genes
BARD1 mystery: tumor suppressors are cancer susceptibility genes
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The full-length BRCA1-associated RING domain 1 (BARD1) gene encodes a 777-aa protein. BARD1 displays a dual role in cancer development and progression as it acts as a tumor suppressor and an oncogene. Structurally, BARD1 has homologous domains to BRCA1 that aid their heterodimer interaction to inhibit the progression of different cancers such as br...
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Full title
BARD1 mystery: tumor suppressors are cancer susceptibility genes
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TN_cdi_doaj_primary_oai_doaj_org_article_a6082ff45d8b4d468e7c52be8ebeb5dc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6082ff45d8b4d468e7c52be8ebeb5dc
Other Identifiers
ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-022-09567-4
