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Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reve...

Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reve...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6552716ae754941bec316fd4f082a50

Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy

About this item

Full title

Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy

Publisher

England: The Company of Biologists Ltd

Journal title

Disease models & mechanisms, 2019-03, Vol.12 (3)

Language

English

Formats

Publication information

Publisher

England: The Company of Biologists Ltd

More information

Scope and Contents

Contents

Paneth cells are key epithelial cells providing an antimicrobial barrier and maintaining integrity of the small intestinal stem cell niche. Paneth cell abnormalities are unfortunately detrimental to gut health and often associated with digestive pathologies such as Crohn's disease or infections. Similar alterations are observed in individuals with...

Alternative Titles

Full title

Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a6552716ae754941bec316fd4f082a50

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6552716ae754941bec316fd4f082a50

Other Identifiers

ISSN

1754-8403,1754-8411

E-ISSN

1754-8411

DOI

10.1242/dmm.037069

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