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Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity i...

Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a66fce3304bf486a94ff19d582035a16

Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity in mice by gene gun vaccines against E. coli beta-galactosidase

About this item

Full title

Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity in mice by gene gun vaccines against E. coli beta-galactosidase

Publisher

United States: Public Library of Science (PLoS)

Journal title

PloS one, 2014, Vol.9 (7), p.e102280

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science (PLoS)

More information

Scope and Contents

Contents

The type of immune response is critical for successful protection and typically determined by pathogen-associated danger molecules. In contrast, protein antigens are usually regarded as passive target structures. Here, we provide evidence that the structure of the antigen can profoundly influence the type of response that is elicited under else ide...

Alternative Titles

Full title

Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity in mice by gene gun vaccines against E. coli beta-galactosidase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a66fce3304bf486a94ff19d582035a16

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a66fce3304bf486a94ff19d582035a16

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0102280

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