Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity i...
Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity in mice by gene gun vaccines against E. coli beta-galactosidase
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United States: Public Library of Science (PLoS)
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English
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United States: Public Library of Science (PLoS)
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The type of immune response is critical for successful protection and typically determined by pathogen-associated danger molecules. In contrast, protein antigens are usually regarded as passive target structures. Here, we provide evidence that the structure of the antigen can profoundly influence the type of response that is elicited under else ide...
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Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity in mice by gene gun vaccines against E. coli beta-galactosidase
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TN_cdi_doaj_primary_oai_doaj_org_article_a66fce3304bf486a94ff19d582035a16
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a66fce3304bf486a94ff19d582035a16
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0102280