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A Peripheral Blood Signature of Increased Th1 and Myeloid Cells Combined with Serum Inflammatory Med...

A Peripheral Blood Signature of Increased Th1 and Myeloid Cells Combined with Serum Inflammatory Med...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6981a7ead1247d6a980be087c5c8d93

A Peripheral Blood Signature of Increased Th1 and Myeloid Cells Combined with Serum Inflammatory Mediators Is Associated with Response to Abatacept in Rheumatoid Arthritis Patients

About this item

Full title

A Peripheral Blood Signature of Increased Th1 and Myeloid Cells Combined with Serum Inflammatory Mediators Is Associated with Response to Abatacept in Rheumatoid Arthritis Patients

Publisher

Switzerland: MDPI AG

Journal title

Cells (Basel, Switzerland), 2023-12, Vol.12 (24), p.2808

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Abatacept (CTLA4-Ig)—a monoclonal antibody which restricts T cell activation—is an effective treatment for rheumatoid arthritis (RA). Nevertheless, only 50% of RA patients attain clinical responses, while predictors of response are rather limited. Herein, we aimed to investigate for early biomarkers of response to abatacept, based on a detailed imm...

Alternative Titles

Full title

A Peripheral Blood Signature of Increased Th1 and Myeloid Cells Combined with Serum Inflammatory Mediators Is Associated with Response to Abatacept in Rheumatoid Arthritis Patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a6981a7ead1247d6a980be087c5c8d93

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6981a7ead1247d6a980be087c5c8d93

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells12242808

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