Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequenc...
Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Understanding the complex background of cancer requires genotype-phenotype information in single-cell resolution. Here, we perform long-read single-cell RNA sequencing (scRNA-seq) on clinical samples from three ovarian cancer patients presenting with omental metastasis and increase the PacBio sequencing depth to 12,000 reads per cell. Our approach...
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Full title
Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_a6ca4dd2f21440459a66c8a701729688
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6ca4dd2f21440459a66c8a701729688
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-43387-9
