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Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet a...

Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6f32b648c0c472dbb866e3e6fecad9a

Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration

About this item

Full title

Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration

Publisher

Brazil: Associação Brasileira de Divulgação Científica

Journal title

Brazilian journal of medical and biological research, 2025-01, Vol.58, p.e14187

Language

English

Formats

Publication information

Publisher

Brazil: Associação Brasileira de Divulgação Científica

More information

Scope and Contents

Contents

Age-related macular degeneration (AMD), particularly the wet form characterized by choroidal neovascularization, is a leading cause of vision loss. Dysregulation of regulatory T cells (Tregs), key modulators of inflammatory responses, may contribute to wet AMD pathogenesis. This study explored the involvement of Tregs and the Rac1 signaling pathway...

Alternative Titles

Full title

Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a6f32b648c0c472dbb866e3e6fecad9a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6f32b648c0c472dbb866e3e6fecad9a

Other Identifiers

ISSN

0100-879X,1414-431X

E-ISSN

1414-431X

DOI

10.1590/1414-431x2024e14187

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