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Multiplex imaging relates quantal glutamate release to presynaptic Ca2+ homeostasis at multiple syna...

Multiplex imaging relates quantal glutamate release to presynaptic Ca2+ homeostasis at multiple syna...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6f687718ebe47d89abfb1ed664dd4fb

Multiplex imaging relates quantal glutamate release to presynaptic Ca2+ homeostasis at multiple synapses in situ

About this item

Full title

Multiplex imaging relates quantal glutamate release to presynaptic Ca2+ homeostasis at multiple synapses in situ

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-03, Vol.10 (1), p.1414-14, Article 1414

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Information processing by brain circuits depends on Ca
2+
-dependent, stochastic release of the excitatory neurotransmitter glutamate. Whilst optical glutamate sensors have enabled detection of synaptic discharges, understanding presynaptic machinery requires simultaneous readout of glutamate release and nanomolar presynaptic Ca
2+
in s...

Alternative Titles

Full title

Multiplex imaging relates quantal glutamate release to presynaptic Ca2+ homeostasis at multiple synapses in situ

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a6f687718ebe47d89abfb1ed664dd4fb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6f687718ebe47d89abfb1ed664dd4fb

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-09216-8

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