Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequ...
Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression
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Author / Creator
Ghallab, Ahmed , Myllys, Maiju , Friebel, Adrian , Duda, Julia , Edlund, Karolina , Halilbasic, Emina , Vucur, Mihael , Hobloss, Zaynab , Brackhagen, Lisa , Begher-Tibbe, Brigitte , Hassan, Reham , Burke, Michael , Genc, Erhan , Frohwein, Lynn Johann , Hofmann, Ute , Holland, Christian H. , González, Daniela , Keller, Magdalena , Seddek, Abdel-latif , Abbas, Tahany , Mohammed, Elsayed S. I. , Teufel, Andreas , Itzel, Timo , Metzler, Sarah , Marchan, Rosemarie , Cadenas, Cristina , Watzl, Carsten , Nitsche, Michael A. , Kappenberg, Franziska , Luedde, Tom , Longerich, Thomas , Rahnenführer, Jörg , Hoehme, Stefan , Trauner, Michael and Hengstler, Jan G.
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Mouse models of non-alcoholic fatty liver disease (NAFLD) are required to define therapeutic targets, but detailed time-resolved studies to establish a sequence of events are lacking. Here, we fed male C57Bl/6N mice a Western or standard diet over 48 weeks. Multiscale time-resolved characterization was performed using RNA-seq, histopathology, immun...
Alternative Titles
Full title
Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression
Authors, Artists and Contributors
Author / Creator
Myllys, Maiju
Friebel, Adrian
Duda, Julia
Edlund, Karolina
Halilbasic, Emina
Vucur, Mihael
Hobloss, Zaynab
Brackhagen, Lisa
Begher-Tibbe, Brigitte
Hassan, Reham
Burke, Michael
Genc, Erhan
Frohwein, Lynn Johann
Hofmann, Ute
Holland, Christian H.
González, Daniela
Keller, Magdalena
Seddek, Abdel-latif
Abbas, Tahany
Mohammed, Elsayed S. I.
Teufel, Andreas
Itzel, Timo
Metzler, Sarah
Marchan, Rosemarie
Cadenas, Cristina
Watzl, Carsten
Nitsche, Michael A.
Kappenberg, Franziska
Luedde, Tom
Longerich, Thomas
Rahnenführer, Jörg
Hoehme, Stefan
Trauner, Michael
Hengstler, Jan G.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a6f74a2737334541a4a2a3c5ced62fe0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6f74a2737334541a4a2a3c5ced62fe0
Other Identifiers
ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells10102516