The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced ac...
The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Acetaminophen (APAP) is the main cause of acute liver failure in the West. Specific efficacious therapies for acute liver failure (ALF) are limited and time-dependent. The mechanisms that drive irreversible acute liver failure remain poorly characterized. Here we report that the recently discovered platelet receptor CLEC-2 (C-type lectin-like recep...
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The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure
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TN_cdi_doaj_primary_oai_doaj_org_article_a6f8dbdcb34b42c0a82ada447cf8eac9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a6f8dbdcb34b42c0a82ada447cf8eac9
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15584-3
