Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treate...
Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer
About this item
Full title
Author / Creator
Pereira, Bernard , Chen, Christopher T. , Goyal, Lipika , Walmsley, Charlotte , Pinto, Christopher J. , Baiev, Islam , Allen, Read , Henderson, Laura , Saha, Supriya , Reyes, Stephanie , Taylor, Martin S. , Fitzgerald, Donna M. , Broudo, Maida Williams , Sahu, Avinash , Gao, Xin , Winckler, Wendy , Brannon, A. Rose , Engelman, Jeffrey A. , Leary, Rebecca , Stone, James R. , Campbell, Catarina D. and Juric, Dejan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In patients with metastatic cancer, spatial heterogeneity of somatic alterations may lead to incomplete assessment of a cancer’s mutational profile when analyzing a single tumor biopsy. In this study, we perform sequencing of cell-free DNA (cfDNA) and distinct metastatic tissue samples from ten rapid autopsy cases with pre-treated metastatic cancer...
Alternative Titles
Full title
Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer
Authors, Artists and Contributors
Author / Creator
Chen, Christopher T.
Goyal, Lipika
Walmsley, Charlotte
Pinto, Christopher J.
Baiev, Islam
Allen, Read
Henderson, Laura
Saha, Supriya
Reyes, Stephanie
Taylor, Martin S.
Fitzgerald, Donna M.
Broudo, Maida Williams
Sahu, Avinash
Gao, Xin
Winckler, Wendy
Brannon, A. Rose
Engelman, Jeffrey A.
Leary, Rebecca
Stone, James R.
Campbell, Catarina D.
Juric, Dejan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a702ab2e73e84ce88013c89389a381ef
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a702ab2e73e84ce88013c89389a381ef
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-23394-4
