Utilizing molecular docking and cell validation to explore the potential mechanisms of lupenone atte...
Utilizing molecular docking and cell validation to explore the potential mechanisms of lupenone attenuating the inflammatory response via NF‐κB pathway
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Author / Creator
Wang, Xiangpei , Liu, Mei , Li, Xiaofen , Zhang, Mei , Xu, Feng , Liu, Hongyun and Wu, Hongmei
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Diabetic nephropathy (DN), a common microvascular complicating disease of diabetes. Lupenone, a pentacyclic triterpenoid, has anti-inflammatory effects and can prevent type 2 diabetes mellitus and treat renal damage, however, the effects and mechanisms of lupenone in DN remain unclear. Thereby,the MTT method was used to investigate the antiprolifer...
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Full title
Utilizing molecular docking and cell validation to explore the potential mechanisms of lupenone attenuating the inflammatory response via NF‐κB pathway
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TN_cdi_doaj_primary_oai_doaj_org_article_a70fc71227934e6c82f669aab714e704
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a70fc71227934e6c82f669aab714e704
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-51150-3