FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neu...
FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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England: eLife Science Publications, Ltd
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English
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England: eLife Science Publications, Ltd
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Neurons rely on translation of synaptic mRNAs in order to generate activity-dependent changes in plasticity. Here, we develop a strategy combining compartment-specific crosslinking immunoprecipitation (CLIP) and translating ribosome affinity purification (TRAP) in conditionally tagged mice to precisely define the ribosome-bound dendritic transcript...
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Full title
FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_a7355e8c3b06440880d93b72cabe9183
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7355e8c3b06440880d93b72cabe9183
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.71892
