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Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation

Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a758cf7e3e61420a87ab6cf63bc5d18d

Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation

About this item

Full title

Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-08, Vol.7 (1), p.1-9, Article 7621

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Under ischemic conditions, tissues are exposed to hypoxia. Although human physiology, to a certain extent, can adapt to hypoxic conditions, the impact of low oxygen levels on platelet function is unresolved. Therefore, we explored how reduction of atmospheric oxygen levels to 1% might affect agonist-induced aggregation and static adhesion of isolat...

Alternative Titles

Full title

Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a758cf7e3e61420a87ab6cf63bc5d18d

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a758cf7e3e61420a87ab6cf63bc5d18d

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-07988-x

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