Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation
Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Under ischemic conditions, tissues are exposed to hypoxia. Although human physiology, to a certain extent, can adapt to hypoxic conditions, the impact of low oxygen levels on platelet function is unresolved. Therefore, we explored how reduction of atmospheric oxygen levels to 1% might affect agonist-induced aggregation and static adhesion of isolat...
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Hypoxia impairs agonist-induced integrin αIIbβ3 activation and platelet aggregation
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TN_cdi_doaj_primary_oai_doaj_org_article_a758cf7e3e61420a87ab6cf63bc5d18d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a758cf7e3e61420a87ab6cf63bc5d18d
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-07988-x