Human single cell RNA-sequencing reveals a targetable CD8+ exhausted T cell population that maintain...
Human single cell RNA-sequencing reveals a targetable CD8+ exhausted T cell population that maintains mouse low-grade glioma growth
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In solid cancers, T cells typically function as cytotoxic effectors to limit tumor growth, prompting therapies that capitalize upon this antineoplastic property (immune checkpoint inhibition; ICI). Unfortunately, ICI treatments have been largely ineffective for high-grade brain tumors (gliomas; HGGs). Leveraging several single-cell RNA sequencing d...
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Human single cell RNA-sequencing reveals a targetable CD8+ exhausted T cell population that maintains mouse low-grade glioma growth
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TN_cdi_doaj_primary_oai_doaj_org_article_a76d1fc385104e84bffc95146882c3f4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a76d1fc385104e84bffc95146882c3f4
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-54569-4
