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Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7756ce122b04439b2b330f101fbb2e6

Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

About this item

Full title

Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2020-09, Vol.9

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

To form new blood vessels (angiogenesis), endothelial cells (ECs) must be activated and acquire highly migratory and proliferative phenotypes. However, the molecular mechanisms that govern these processes are incompletely understood. Here, we show that Apelin signaling functions to drive ECs into such an angiogenic state. Zebrafish lacking Apelin s...

Alternative Titles

Full title

Apelin signaling drives vascular endothelial cells toward a pro-angiogenic state

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a7756ce122b04439b2b330f101fbb2e6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7756ce122b04439b2b330f101fbb2e6

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.55589

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