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Suppression of TNBC metastasis by doxazosin, a novel dual inhibitor of c-MET/EGFR

Suppression of TNBC metastasis by doxazosin, a novel dual inhibitor of c-MET/EGFR

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a78d66b75c4a4c13ba43af1a16e5d520

Suppression of TNBC metastasis by doxazosin, a novel dual inhibitor of c-MET/EGFR

About this item

Full title

Suppression of TNBC metastasis by doxazosin, a novel dual inhibitor of c-MET/EGFR

Publisher

London: BioMed Central Ltd

Journal title

Journal of experimental & clinical cancer research, 2023-11, Vol.42 (1), p.1-292, Article 292

Language

English

Formats

Publication information

Publisher

London: BioMed Central Ltd

More information

Scope and Contents

Contents

Background Triple-negative breast cancer (TNBC) is characterized by aggressive growth and a high propensity for recurrence and metastasis. Simultaneous overexpression of c-MET and EGFR in TNBC is associated with worse clinicopathological features and unfavorable outcomes. Although the development of new c-MET inhibitors and the emergence of 3.sup.r...

Alternative Titles

Full title

Suppression of TNBC metastasis by doxazosin, a novel dual inhibitor of c-MET/EGFR

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a78d66b75c4a4c13ba43af1a16e5d520

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a78d66b75c4a4c13ba43af1a16e5d520

Other Identifiers

ISSN

1756-9966,0392-9078

E-ISSN

1756-9966

DOI

10.1186/s13046-023-02866-z

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