Design, Synthesis and Biological Evaluation of Biscarbamates as Potential Selective Butyrylcholinest...
Design, Synthesis and Biological Evaluation of Biscarbamates as Potential Selective Butyrylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease
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Basel: MDPI AG
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Language
English
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Basel: MDPI AG
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As butyrylcholinesterase (BChE) plays a role in the progression of symptoms and pathophysiology of Alzheimer’s disease (AD), selective inhibition of BChE over acetylcholinesterase (AChE) can represent a promising pathway in treating AD. The carbamate group was chosen as a pharmacophore because the carbamates currently or previously in use for the t...
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Design, Synthesis and Biological Evaluation of Biscarbamates as Potential Selective Butyrylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease
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TN_cdi_doaj_primary_oai_doaj_org_article_a7963318431d4bbd97d70547ea52cf14
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7963318431d4bbd97d70547ea52cf14
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ISSN
1424-8247
E-ISSN
1424-8247
DOI
10.3390/ph15101220
