Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expr...
Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression
About this item
Full title
Author / Creator
Cuomo, Anna S. E. , Seaton, Daniel D. , McCarthy, Davis J. , Martinez, Iker , Bonder, Marc Jan , Garcia-Bernardo, Jose , Amatya, Shradha , Madrigal, Pedro , Isaacson, Abigail , Buettner, Florian , Knights, Andrew , Natarajan, Kedar Nath , Vallier, Ludovic , Marioni, John C. , Chhatriwala, Mariya , Stegle, Oliver and HipSci Consortium
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Recent developments in stem cell biology have enabled the study of cell fate decisions in early human development that are impossible to study in vivo. However, understanding how development varies across individuals and, in particular, the influence of common genetic variants during this process has not been characterised. Here, we exploit human i...
Alternative Titles
Full title
Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression
Authors, Artists and Contributors
Author / Creator
Seaton, Daniel D.
McCarthy, Davis J.
Martinez, Iker
Bonder, Marc Jan
Garcia-Bernardo, Jose
Amatya, Shradha
Madrigal, Pedro
Isaacson, Abigail
Buettner, Florian
Knights, Andrew
Natarajan, Kedar Nath
Vallier, Ludovic
Marioni, John C.
Chhatriwala, Mariya
Stegle, Oliver
HipSci Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a7b1f1030ed944ff83690e903da90113
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7b1f1030ed944ff83690e903da90113
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-14457-z
